📝 빈칸추론
다음 빈칸에 들어갈 말로 가장 적절한 것을 고르시오.
The accumulation of metabolic waste within neural tissue exposes a striking oversight in our understanding of cognitive decline. When examining this process, a striking pattern emerges: the brain possesses no conventional lymphatic drainage, yet somehow maintains remarkably clean interstitial spaces during healthy periods. Take the case where cerebrospinal fluid flows along perivascular channels surrounding blood vessels, driven by arterial pulsations and facilitated through specialized water channels on support cell membranes. If this hydraulic clearance operates efficiently, toxic protein aggregates are flushed away before they can form the pathological deposits characteristic of degenerative conditions. In contrast, disrupting these fluid dynamics through sleep deprivation or vascular dysfunction rapidly leads to measurable accumulation of neurotoxic species. Thus, the sophisticated cognitive architecture we possess today was created not by enhanced computational capacity of neurons, but by _________________________. Picture a scenario in which intellectual performance deteriorates not from neuronal death itself, but from gradual suffocation under uncleared debris.
①
preventing toxic protein aggregates from forming pathological deposits
②
hydraulic clearance along perivascular channels surrounding blood vessels
③
enhanced synaptic plasticity and neuronal computational processing capacity
④
specialized water channels facilitating cerebrospinal fluid transport mechanisms
⑤
the relentless mechanical efficiency of waste removal systems